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KMID : 0613820070170020218
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Journal of Life Science
2007 Volume.17 No. 2 p.218 ~ p.222
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Relationship between HsCRP and Pulse Transit Time
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Kim Yun-Jin
Min Hong-Gi
Kim Young-Joo
Jeon Ah-Young
Jeon Gye-Rok
Ye Soo-Young
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Abstract
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The purpose of this study is to evaluate the relationship between high sensitive C-reactive protein (hsCRP) and pulse transit time (PPT). Apparently healthy 233 subjects had been enrolled in the health promotion center of the Pusan National University Hospital from Jan. 29 to Feb. 26, 2004. They had no previous history of diabetes, hypertension and hyperlipidemia. Subjects were categorized according to tertiles of hsCRP level [Group 1: first tertile (0.01 ~ 0.02 ㎎/dl), Group 2: second tertile (0.03 ~ 0.05 ㎎/dl), Group 3: third tertile (0.06 ~ 0.12 ㎎/dl), and Group 4: Fourth tertile (0.13 ~ 16.8 ㎎/dl)]. PTT, body mass index (BMI), total cholesterol (T-C), LDL-cholesterol (LDL-C), blood sugar (BS), systolic blood pressure (sBP) and diastolic blood pressure (dBP) were significantly different among hsCRP groups (p＜0.05). HsCRP is positively related with BMI, tryglyceride (TG), LDL, sBP and dBP (p＜0.05), and negatively related with PTT and HDL-cholesterol (HDL-C) (p＜0.05). PTT is significantly negatively related with hsCRP, T-C, TG, LDL-C, BS, dBP and sBP (p＜0.05). The hsCRP and PTT were related before controlling BMI, T-C, LDL-C, sBP, and dBP, but not related after controlling. The relationship between hsCRP and PTT depends on cardiovascular disease risk factors.
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KEYWORD
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hsCRP, pulse transit time, atherosclerosis, cardiovascular disease, risk factor
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